Treat-to-Target Urate-Lowering Treatment and Cardiovascular Outcomes in Patients With Gout
In this cohort study among patients with gout who were newly prescribed ULT, achieving serum urate levels lower than 6 mg/dL within 12 months was associated with a lower 5-year risk of major adverse cardiovascular events.
Authors
- P. Drivelegka (ORCID: https://orcid.org/0000-0002-2349-8820)
- Tatiana Zverkova Sandström (ORCID: https://orcid.org/0000-0001-9478-2354)
- Mats Dehlin (ORCID: https://orcid.org/0000-0001-5165-0968)
- Edoardo Cipolletta (ORCID: https://orcid.org/0000-0002-6881-8197)
- Laila J. Tata (ORCID: https://orcid.org/0000-0002-6404-8658)
- D. Rozza
- Georgina Nakafero (ORCID: https://orcid.org/0000-0002-3859-7354)
- A. Avery
- Clémence Leyrat (ORCID: https://orcid.org/0000-0002-4097-4577)
- Abhishek Abhishek (ORCID: https://orcid.org/0000-0003-0121-4919)
- Mamas A. Mamas
Institutions
- Marche Polytechnic University (IT)
- University of Nottingham (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Società Italiana di Reumatologia (IT)
- Nottingham Biomedical Research Centre (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
- Keele University (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- JAMA Internal Medicine
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1001/jamainternmed.2025.7453
- Citations
- 2
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 69.88