Donation After Circulatory Death Heart Transplant Without Preimplant Reanimation Using Rapid Ultraoxygenated Recovery
This study demonstrates the safety, feasibility, and efficacy of REUP for DCD heart recovery without donor heart reanimation in a broad population of donors and recipients and without regard to anticipated ischemic time. Given the high cost and complexity of current DCD heart recovery strategies, as well as ethical concerns surrounding normothermic regional perfusion, REUP may prove to be a promising procurement method. Further study is required to support continued expansion of this novel technique.
Authors
- Hasan K. Siddiqi (ORCID: https://orcid.org/0000-0002-2274-9405)
- Tarek Absi (ORCID: https://orcid.org/0000-0002-6777-6132)
- DAWN M PEDROTTY
- Swaroop Bommareddi
- Marshall D Brinkley
- Stacy Tsai (ORCID: https://orcid.org/0009-0004-3566-9799)
- Brian D. Lima
- Aniket S. Rali (ORCID: https://orcid.org/0000-0002-3778-9979)
- John M. Trahanas (ORCID: https://orcid.org/0000-0001-8644-5489)
- Jonathan N. Menachem (ORCID: https://orcid.org/0000-0003-4787-1906)
- Suzanne Sacks
- Awab Ahmad
- Sandip Zalawadiya
- Kevin C. McGann
- Chen Chia Wang
- Mias Pretorious
- Joey Lepore
- Mark Petrovic
- Matthew Bacchetta
- Kaushik Amancherla
- Joshua Lowman
- Aaron M. Williams
- Ashish S. Shah
- Stephen Devries
- Eric Quintana
Institutions
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1001/jama.2025.25169
- Citations
- 5
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 195.73