Real-Time ATP Imaging Reveals the Metabolic State During Branching Nephrogenesis

UB branching was heavily dependent on glycolysis, and UB cells in the early branching phase were more sensitive to glycolytic inhibition than mesenchyme cells are. These results highlight the significance of metabolic regulation in branching nephrogenesis.

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Publication Details

Journal
Kidney360
Published
2026-01-26
DOI
https://doi.org/10.34067/kid.0000001148
Primary Topic
Renal and related cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-Time ATP Imaging Reveals the Metabolic State During Branching Nephrogenesis

Akira Shimizu, Shunsuke Yamamoto, Masamichi Yamamoto, S. Fukuma et al.
Kidney360
Renal and related cancers
article

Real-Time ATP Imaging Reveals the Metabolic State During Branching Nephrogenesis

Akira Shimizu, Shunsuke Yamamoto, Masamichi Yamamoto, S. Fukuma, Motoko Yanagita, Akiko Mii, H. Imamura
article en

Abstract

UB branching was heavily dependent on glycolysis, and UB cells in the early branching phase were more sensitive to glycolytic inhibition than mesenchyme cells are. These results highlight the significance of metabolic regulation in branching nephrogenesis.

Kidney360
Kyoto University (JP), Nippon Medical School (JP)
Openalex Percentile: Top 78%
Renal and related cancers
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