Shenqi compound enhances pancreatic β-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathway

SQC promotes the maturation and transport of insulin secretory vesicles, thereby enhancing the secretory function of INS-1 cells in response to high glucose-induced damage. This protective effect may be associated with the activation of the NOD1/RIP2 signaling pathway.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-01-26
DOI
https://doi.org/10.3389/fnut.2025.1690849
Primary Topic
Pancreatic function and diabetes
Type
article
Field-Weighted Citation Impact
0.00

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article

Shenqi compound enhances pancreatic β-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathway

Ruobing Tang, X.L. Zhang, Chunguang Xie, Nanyu Yao et al.
Frontiers in Nutrition
Pancreatic function and diabetes
article

Shenqi compound enhances pancreatic β-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathway

Ruobing Tang, X.L. Zhang, Chunguang Xie, Nanyu Yao, Yiqian Xing, Qiyue Yang, Ya Liu
article en

Abstract

SQC promotes the maturation and transport of insulin secretory vesicles, thereby enhancing the secretory function of INS-1 cells in response to high glucose-induced damage. This protective effect may be associated with the activation of the NOD1/RIP2 signaling pathway.

Frontiers in NutritionVol. 12
Jimo District Qingdao Hospital of Traditional Chinese Medicine (CN), Chengdu University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 77%
Pancreatic function and diabetes
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