Interactive effect of retinal microvascular impairment and larger lesion diameter on cognitive impairment in lacunar infarction
The diameter of the lesion infarct and severity of retinal microvascular damage may jointly reflect global cognitive performance in LI, signifying ischemia as a potential shared mechanism. Integrating retinal imaging with neuroimaging may enhance early risk stratification and personalized intervention strategies.
Authors
- Huihua Qiu
- Zheli Chen
- Jiahui Chen (ORCID: https://orcid.org/0009-0006-3847-8298)
- Carol Y. Cheung
- Yuntao Liu
- Yimo Guo
- Chunwen Zheng
- Ip Yiu Ming Bonaventure
- William Robert Kwapong
- Haoran Cheng
- Zhen Wang
Institutions
- Chinese University of Hong Kong (HK)
- Capital Medical University (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Third People's Hospital of Huzhou (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1186/s13195-026-01959-z
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00