These aren’t the beliefs you’re looking for: on the limits of affect-neutral accounts of psychedelic therapy

A recurring finding in psychedelic-assisted therapy is that the subjective intensity and quality of the psychedelic experience contribute more to therapeutic outcomes than the administered dose. To explain why such experiences are therapeutic, many have appealed to what these may reveal or enable, such as the types of mental representations that can be acquired, the expansion of what can enter awareness, or the revision of high-level beliefs about the self and the world. Across these proposals, some form of belief disruption is often assigned a causal role. In this paper, I argue that even if psychedelics do work by loosening beliefs or expanding awareness, this alone is not sufficient to explain why the resulting changes should be beneficial rather than neutral or harmful. By implicitly taking for granted the typically positive character of many psychedelic experiences, existing theories risk describing processes that could just as easily worsen distress as alleviate it, and so fail to reflect the literature’s predominantly positive outcomes. Ultimately, I argue that without a positive shift in affective valence, there is no clear reason why psychedelic experiences should lead to therapeutic outcomes.

Authors

Institutions

Publication Details

Journal
Synthese
Published
2026-01-26
DOI
https://doi.org/10.1007/s11229-026-05443-x
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

These aren’t the beliefs you’re looking for: on the limits of affect-neutral accounts of psychedelic therapy

Celia R. Blaise
Synthese
Psychedelics and Drug Studies
article

These aren’t the beliefs you’re looking for: on the limits of affect-neutral accounts of psychedelic therapy

Celia R. Blaise
article en

Abstract

A recurring finding in psychedelic-assisted therapy is that the subjective intensity and quality of the psychedelic experience contribute more to therapeutic outcomes than the administered dose. To explain why such experiences are therapeutic, many have appealed to what these may reveal or enable, such as the types of mental representations that can be acquired, the expansion of what can enter awareness, or the revision of high-level beliefs about the self and the world. Across these proposals, some form of belief disruption is often assigned a causal role. In this paper, I argue that even if psychedelics do work by loosening beliefs or expanding awareness, this alone is not sufficient to explain why the resulting changes should be beneficial rather than neutral or harmful. By implicitly taking for granted the typically positive character of many psychedelic experiences, existing theories risk describing processes that could just as easily worsen distress as alleviate it, and so fail to reflect the literature’s predominantly positive outcomes. Ultimately, I argue that without a positive shift in affective valence, there is no clear reason why psychedelic experiences should lead to therapeutic outcomes.

SyntheseVol. 207(2)
University of Glasgow (GB), University of Sheffield (GB)
Openalex Percentile: Top 79%
Psychedelics and Drug Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

These aren’t the beliefs you’re looking for: on the limits of affect-neutral accounts of psychedelic therapy — Celia R. Blaise · Synthese (2026) | TGRS Research Map | TGRS