Immunosuppressive immune microenvironment landscapes in VISTA-high gastric cancer
Our findings establish VISTA as a central immunoregulatory checkpoint in gastric cancer, suggesting its potential as a promising therapeutic target for combination immunotherapeutic approaches.
Authors
- Dan Liu
- Yiming Luo
- Y. Xie
- Haoxin Peng
- L. Shen
- Yakun Wang
- Yu Sun
- Zhi Peng
- Yang Chen
- Xiaotian Zhang
- Qian Yao
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1038/s41416-025-03290-0
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- National Natural Science Foundation of China
- Peking University
- National Science and Technology Major Project
- Wu Jieping Medical Foundation
- Fundamental Research Funds for the Central Universities