Fifteen-day topical ketorolac tromethamine, with and without benzalkonium chloride, alters tear function, goblet cell density, and meibomian gland integrity in healthy cats
Both ketorolac formulations reduced STT, TFBT, and GCD, supporting the development of a qualitative dry eye state in healthy cats. BACKT resulted in greater ocular discomfort, increased MG loss, and higher lipid peroxidation, indicating BAC-related cytotoxicity. Caution is advised when prescribing prolonged topical ketorolac, and concurrent ocular lubrication is recommended.
Authors
- Nathália de Assis Pereira (ORCID: https://orcid.org/0000-0002-4045-9073)
- Bruna Carvalho Silveira (ORCID: https://orcid.org/0000-0002-4385-5709)
- Alexandre Pinto Ribeiro (ORCID: https://orcid.org/0000-0002-8922-2886)
- Anderson Oliveira Souza
- Douglas Lisboa Ramalho
- Maria Gabriela de Mendonça Mazetti
- Nataliê Ecker (ORCID: https://orcid.org/0009-0007-9456-7735)
- Matheus Anthony Mendes
Institutions
- Universidade Federal de Mato Grosso (BR)
Publication Details
- Journal
- Veterinary World
- Published
- 2026-01-25
- DOI
- https://doi.org/10.14202/vetworld.2026.310-323
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00