Impaired systemic antibody response against gut microbiota pathobionts in critical illness and susceptibility to nosocomial infections
These findings indicate that the systemic antibody barrier against microbiota pathobionts is compromised in critical illness and associated with increased risk of nosocomial infections.
Authors
- Jared Schlechte
- Ian-Ling Yu
- Nicole A. Cho
- Braedon McDonald (ORCID: https://orcid.org/0000-0001-8936-8992)
- Tanner Fahlman
- Colin Mackenzie
- Ish Bains
Institutions
- University of Calgary (CA)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2026-01-27
- DOI
- https://doi.org/10.1186/s40635-026-00860-1
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cumming School of Medicine, University of Calgary
- Canadian Institutes of Health Research