Analysis of ASMs and male infertility using the FDA adverse event reporting system (FAERS)

Despite the limitations of the FAERS database, these findings emphasize the importance of monitoring reproductive health in male patients, particularly those of childbearing age, and highlight the need to balance ASM efficacy with potential reproductive toxicity in clinical practice. Further research is needed to validate these findings and explore underlying mechanisms.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-01-26
DOI
https://doi.org/10.3389/fpubh.2025.1738546
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Analysis of ASMs and male infertility using the FDA adverse event reporting system (FAERS)

Xuezhi Liang, Yujia Xi, Kunyang An, Xinfang Cao et al.
Frontiers in Public Health
Pharmacological Effects and Toxicity Studies
article

Analysis of ASMs and male infertility using the FDA adverse event reporting system (FAERS)

Xuezhi Liang, Yujia Xi, Kunyang An, Xinfang Cao, Jingqi Wang, Xiaoqin Hu, Jingyu Xu
article en

Abstract

Despite the limitations of the FAERS database, these findings emphasize the importance of monitoring reproductive health in male patients, particularly those of childbearing age, and highlight the need to balance ASM efficacy with potential reproductive toxicity in clinical practice. Further research is needed to validate these findings and explore underlying mechanisms.

Frontiers in Public HealthVol. 13
Shanxi Medical University (CN), First Hospital of Shanxi Medical University (CN), Second Hospital of Shanxi Medical University (CN)
Gender equality
Openalex Percentile: Top 78%
Pharmacological Effects and Toxicity Studies
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