Effect of Testosterone on Maintenance of Morphine-induced Conditioned Place Preference: Androgen and μ-opioid Receptor Gene Expressions in PFC and NAc of Rats
Our data indicated that decreased level of testosterone facilitates extinction period in morphine CPP model in male rats. This result could be due to the changes in the expression of opioid and androgenic receptors in PFC and NAc. This study confirms the crucial role of androgen system in modulating drug reward.
Authors
- Nasim Vousooghi (ORCID: https://orcid.org/0000-0002-3392-3640)
- Nader Charkhgard (ORCID: https://orcid.org/0000-0003-1987-8705)
- Maryam Farahmandfar
- Maryam Zahmatkesh (ORCID: https://orcid.org/0000-0002-8950-893X)
- Anahita Torkaman-Boutorabi
- Nasim Nadi Moghadam
Institutions
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Clinical Psychopharmacology and Neuroscience
- Published
- 2026-01-26
- DOI
- https://doi.org/10.9758/cpn.25.1348
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00