Epigenetic sperm quality testing for predicting fertility treatment success: a real-world and multi-site analysis

This real-world analysis was limited by the availability of detailed clinical and phenotypic data, which may introduce potential confounders. Nevertheless, the findings highlight the clinical value of epigenetic sperm assessment as part of male fertility evaluation and support its potential to guide more effective, personalized fertility treatment pathways.

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Publication Details

Journal
Journal of Assisted Reproduction and Genetics
Published
2026-01-26
DOI
https://doi.org/10.1007/s10815-025-03791-0
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Epigenetic sperm quality testing for predicting fertility treatment success: a real-world and multi-site analysis

Kristin Brogaard, Jordan Kassab, L.J. Hansard, S.B. Hudson et al.
Journal of Assisted Reproduction and Genetics
Sperm and Testicular Function
article

Epigenetic sperm quality testing for predicting fertility treatment success: a real-world and multi-site analysis

Kristin Brogaard, Jordan Kassab, L.J. Hansard, S.B. Hudson, Carrie E. Bedient, K. Kaskar, Kaylen M. Silverberg, Valerie I. Shavell, R.H. Miller, Kristin Van Heertum, Madeline Kaye, Nirvika Singh, Bryce Daines, Lipshultz Li, Abby C Eblen, Andrew Olson, Mili Thakur, Lorry Schneider, Alexis Reynolds, Matthew VerMilyea, Derek Petersen, Meghan Smith, Lakingya Robinson, Emma Giuliani, Amy Schutt
article en

Abstract

This real-world analysis was limited by the availability of detailed clinical and phenotypic data, which may introduce potential confounders. Nevertheless, the findings highlight the clinical value of epigenetic sperm assessment as part of male fertility evaluation and support its potential to guide more effective, personalized fertility treatment pathways.

Journal of Assisted Reproduction and Genetics
Brigham Young University (US), Grand Rapids Community College (US), Baylor College of Medicine (US), Deseret Laboratories (United States) (US), Texas Fertility Center (US), Fertility Center of Las Vegas (US), Grand Rapids Public Museum (US), Nashville Oncology Associates (US), Ovation Fertility (US), Shady Grove Fertility Center (US)
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Openalex Percentile: Top 79%
Sperm and Testicular Function
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