Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More than Other Broad Autism Phenotype Traits

Our analysis elucidates the genetic architecture and interaction of ASD and language-related phenotypes. In addition, we reported a number of high-confidence candidate genes within the top linkage regions. These genes will provide insights into the genetic etiology of neurodevelopmental disorders.

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Publication Details

Journal
Genes
Published
2026-01-25
DOI
https://doi.org/10.3390/genes17020125
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More than Other Broad Autism Phenotype Traits

Sherri Wilson, Linda M. Brzustowicz, Christine Gwin, Mudassir Lodi et al.
Genes
Autism Spectrum Disorder Research
article

Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More than Other Broad Autism Phenotype Traits

Sherri Wilson, Linda M. Brzustowicz, Christine Gwin, Mudassir Lodi, Amber Robinson, J. Xing, Christopher W. Bartlett, Judy F. Flax
article en

Abstract

Our analysis elucidates the genetic architecture and interaction of ASD and language-related phenotypes. In addition, we reported a number of high-confidence candidate genes within the top linkage regions. These genes will provide insights into the genetic etiology of neurodevelopmental disorders.

GenesVol. 17(2)
Rutgers, The State University of New Jersey (US), Nationwide Children's Hospital (US), The Ohio State University (US)
Reduced inequalities
Openalex Percentile: Top 79%
Autism Spectrum Disorder Research
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Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More than Other Broad Autism Phenotype Traits — Sherri Wilson, Linda M. Brzustowicz, et al. · Genes (2026) | TGRS Research Map | TGRS