Analysis of <scp> <i>RHD</i> </scp> variant alleles in serologically D‐negative Thai patients: Prevalence and novel discoveries

Our study suggests that PCR and Sanger sequencing for Asian DEL is helpful for serologic D-negative Thai patients, while adsorption/elution is unreliable. WGS, if available, is useful to identify rare and new variants, whereas its cost is not worth for routine testing in the Asian population.

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Publication Details

Journal
Transfusion
Published
2026-01-26
DOI
https://doi.org/10.1111/trf.70090
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of RHD variant alleles in serologically D‐negative Thai patients: Prevalence and novel discoveries

Thunnakhon Sinwatcharaphirom, Patrawadee Pitakpolrat, Suwanna Mekprasan, Pattarin Tangtanatakul et al.
Transfusion
Blood groups and transfusion
article

Analysis of RHD variant alleles in serologically D‐negative Thai patients: Prevalence and novel discoveries

Thunnakhon Sinwatcharaphirom, Patrawadee Pitakpolrat, Suwanna Mekprasan, Pattarin Tangtanatakul, Manon Boonbangyang, Ponlapat Rojnuckarin, Phandee Watanaboonyongchareon, Tuangrat Kumar
article en

Abstract

Our study suggests that PCR and Sanger sequencing for Asian DEL is helpful for serologic D-negative Thai patients, while adsorption/elution is unreliable. WGS, if available, is useful to identify rare and new variants, whereas its cost is not worth for routine testing in the Asian population.

Transfusion
Chulalongkorn University (TH), Mahidol University (TH), King Chulalongkorn Memorial Hospital (TH)
King Chulalongkorn Memorial Hospital, Chulalongkorn University, Faculty of Medicine, Chulalongkorn University
Openalex Percentile: Top 80%
Blood groups and transfusion
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