Active Pediatric Systemic Lupus Erythematosus in Fars Province, Iran: Associations With Geographical and Meteorological Determinants—A Retrospective Cross‑Sectional Study

This study found that living in urban areas and lower annual rainfall are significant risk factors for active pediatric SLE in Fars province, probably due to increased exposure to pollutants and ultraviolet radiation. While previous studies have linked SLE activity to temperature and humidity, no such associations were observed here, highlighting the need for further research on regional environmental influences on SLE.