Binankadsurin A from Kadsura coccinea Fruits Ameliorates Acetaminophen-Induced Liver Injury Through Inhibiting Oxidative Stress by Keap1/Nrf2/HO-1 Pathway
BKA reduces APAP-induced acute liver damage by inhibiting oxidative stress by activating the Keap1/Nrf2/HO-1 signaling pathway, providing a theoretical basis for BKA as a potential therapeutic agent for APAP-induced liver injury.
Authors
- Caiyun Peng
- Muhammad Aamer
- Yashi Wang
- Chuanle Li
- Siméon F. Kouam (ORCID: https://orcid.org/0000-0003-0191-0527)
- Huanghe Yu
- Yupei Yang
- Wei Wang
- Guy Paulin M. Kemayou
- Shiqi Liu
- Bin Li
Institutions
- Université de Yaoundé I (CM)
- Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Nutrients
- Published
- 2026-01-26
- DOI
- https://doi.org/10.3390/nu18030403
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China