Association of novel obesity-related lipid markers with diabetes prevalence in high-risk middle-aged and older adults with cardiovascular diseases

CVAI, TyG-WHtR, TyG-WC, TyG-BMI, and the C-index were positively associated with diabetes in middle-aged and older adults at high cardiovascular risk. CVAI, TyG-WHtR, TyG-WC, and TyG-BMI showed good discriminatory performance for identifying diabetes, with TyG-WC performing best. These TyG-based and obesity-related composite indicators provide feasible options for diabetes identification and risk stratification in high cardiovascular-risk populations and may support population-level screening and prevention efforts in aging societies.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-01-26
DOI
https://doi.org/10.3389/fpubh.2025.1737669
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of novel obesity-related lipid markers with diabetes prevalence in high-risk middle-aged and older adults with cardiovascular diseases

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Frontiers in Public Health
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Association of novel obesity-related lipid markers with diabetes prevalence in high-risk middle-aged and older adults with cardiovascular diseases

Wang Xing-ren, Xue Zhou, Ying Lü, Liying Zhao, Mingsi Chen, Keying Yang, Qiaojun Li
article en

Abstract

CVAI, TyG-WHtR, TyG-WC, TyG-BMI, and the C-index were positively associated with diabetes in middle-aged and older adults at high cardiovascular risk. CVAI, TyG-WHtR, TyG-WC, and TyG-BMI showed good discriminatory performance for identifying diabetes, with TyG-WC performing best. These TyG-based and obesity-related composite indicators provide feasible options for diabetes identification and risk stratification in high cardiovascular-risk populations and may support population-level screening and prevention efforts in aging societies.

Frontiers in Public HealthVol. 13
Hainan Provincial Academy of Agricultural Sciences (CN), Hainan Center for Disease Control & Prevention (CN), Hainan Medical University (CN)
Hainan Medical University
Reduced inequalities
Openalex Percentile: Top 79%
Diabetes, Cardiovascular Risks, and Lipoproteins
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