Longitudinal PFAS exposure and thyroid function trajectories in Taiwanese youth: a 10-year prospective cohort study

PFAS exposure was associated with lower TSH and higher free T4 over 10 years of follow-up, suggesting sustained thyroid-axis perturbation from adolescence into young adulthood. These findings underscore a susceptible developmental window and support long-term biomonitoring and stronger regulatory action where PFAS contamination persists.

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Publication Details

Journal
Environment International
Published
2026-01-26
DOI
https://doi.org/10.1016/j.envint.2026.110106
Primary Topic
Per- and polyfluoroalkyl substances research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal PFAS exposure and thyroid function trajectories in Taiwanese youth: a 10-year prospective cohort study

Ta-Chen Su, Chien-Yu Lin, Hui-Ling Lee
Environment International
Per- and polyfluoroalkyl substances research
article

Longitudinal PFAS exposure and thyroid function trajectories in Taiwanese youth: a 10-year prospective cohort study

Ta-Chen Su, Chien-Yu Lin, Hui-Ling Lee
article en

Abstract

PFAS exposure was associated with lower TSH and higher free T4 over 10 years of follow-up, suggesting sustained thyroid-axis perturbation from adolescence into young adulthood. These findings underscore a susceptible developmental window and support long-term biomonitoring and stronger regulatory action where PFAS contamination persists.

Environment InternationalVol. 208
Fu Jen Catholic University (TW), National Taiwan University Hospital (TW)
Openalex Percentile: Top 79%
Per- and polyfluoroalkyl substances research
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