Complement–Coagulation Axis and Metabolic Dysregulation Underlie the Transition from Mild to Severe Heat Stroke: A Combined Clinical and Proteomic Study

These findings indicate complement- coagalation and metabolic dysregulation drive mild to severe EHS progression, with identified proteins serving as potential biomarkers and therapeutic targets.

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Publication Details

Journal
Shock
Published
2026-01-26
DOI
https://doi.org/10.1097/shk.0000000000002792
Primary Topic
Thermoregulation and physiological responses
Type
article
Field-Weighted Citation Impact
0.00
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article

Complement–Coagulation Axis and Metabolic Dysregulation Underlie the Transition from Mild to Severe Heat Stroke: A Combined Clinical and Proteomic Study

Xiaoai Cao, Xin Cheng, Huimin Niu, YingYing Cao et al.
Shock
Thermoregulation and physiological responses
article

Complement–Coagulation Axis and Metabolic Dysregulation Underlie the Transition from Mild to Severe Heat Stroke: A Combined Clinical and Proteomic Study

Xiaoai Cao, Xin Cheng, Huimin Niu, YingYing Cao, Fei Liu, Nina Cao, Lizhen Wei, Shenghang Zhang, Jinhan Chen
article en

Abstract

These findings indicate complement- coagalation and metabolic dysregulation drive mild to severe EHS progression, with identified proteins serving as potential biomarkers and therapeutic targets.

ShockVol. 65(4)
Fujian Medical University (CN), Shanghai Eighth People Hospital (CN), The Eighth Hospital of Xi'an (CN), Fuzhou University (CN)
Reduced inequalities
Openalex Percentile: Top 79%
Thermoregulation and physiological responses
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