Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias

Low kidney function was associated with elevated blood biomarkers of Alzheimer's disease and related dementia (NfL, GFAP, and A β 40), whereas associations with CSF biomarkers were inconsistent and generally null.

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Publication Details

Journal
Journal of the American Society of Nephrology
Published
2026-01-26
DOI
https://doi.org/10.1681/asn.0000001007
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias

Nele Brusselaers, A. Bruchfeld, Hong Xu, Maria Eriksdotter et al.
Journal of the American Society of Nephrology
Dialysis and Renal Disease Management
article

Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias

Nele Brusselaers, A. Bruchfeld, Hong Xu, Maria Eriksdotter, Juan-Jesus Carrero, Zaixin Zhao, Sara Garcia Ptacek, Yuwei Lin, Nanbo Zhu, Michelle M. Mielke
article en

Abstract

Low kidney function was associated with elevated blood biomarkers of Alzheimer's disease and related dementia (NfL, GFAP, and A β 40), whereas associations with CSF biomarkers were inconsistent and generally null.

Journal of the American Society of Nephrology
Linköping University (SE), Karolinska University Hospital (SE), University of Antwerp (BE), Peking University (CN), Karolinska Institutet (SE), Ghent University (BE), Wake Forest University (US)
Reduced inequalities
Openalex Percentile: Top 80%
Dialysis and Renal Disease Management
DOIOpen Access PDFOpenAlex
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Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias — Nele Brusselaers, A. Bruchfeld, et al. · Journal of the American Society of Nephrology (2026) | TGRS Research Map | TGRS