Differential association of body mass index with hypoglossal nerve stimulation efficacy by pharyngeal collapse pattern in obstructive sleep apnea
The influence of BMI on HGNS treatment response differs meaningfully by pharyngeal collapse phenotype. Incorporating collapse pattern into BMI-based eligibility criteria may improve patient selection and optimize HGNS outcomes.
Authors
- David T. Kent
- Neda Esmaeili (ORCID: https://orcid.org/0009-0008-4956-1497)
- A. Wellman
- Phillip Huyett
- Ludovico Messineo
- SA Sands
- Daniel Vena (ORCID: https://orcid.org/0000-0003-1740-8777)
- Ali Azarbarzin
- Tom Chen
- Eric J Kezirian
- Mark D'Agostino
- Joao LGC Monteiro
Institutions
- Brigham and Women's Hospital (US)
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- Yale University (US)
- Middlesex Hospital (US)
- Harvard Pilgrim Health Care (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-26
- DOI
- https://doi.org/10.64898/2026.01.25.26344734
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Thoracic Society
- Eli Lilly and Company
- Cerebra
- National Institutes of Health
- National Heart, Lung, and Blood Institute