Therapeutic potential of MSCs and their exosomes in hepatic Ischaemia-Reperfusion injury: a systematic review and meta-analysis of rodent studies
MSCs and their exosomes mitigate HIRI through multi-target mechanisms but requires standardized protocols. Future studies should prioritize large-animal validation and translational research to facilitate precision clinical application.
Authors
- Bo Ren (ORCID: https://orcid.org/0000-0001-8332-3611)
- Yanxi Mu
- Wentao Ma (ORCID: https://orcid.org/0000-0002-6762-1093)
- WenCe Zhou
- Cheng Yu (ORCID: https://orcid.org/0000-0002-9227-3764)
- Yusheng Cheng
- Weixiong Zhu
Institutions
- Lanzhou University Second Hospital (CN)
- Gansu Provincial Center for Disease Control and Prevention (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Stem Cells Translational Medicine
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1093/stcltm/szaf078
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China