A randomized controlled trial on the application of a chronic disease management platform based on digital health technology combined with an innovative model of intelligent management for hypertension in patients with hypertension

547 participants completed the study (Intervention: <i>n</i> = 273; Control: <i>n</i> = 274). The intervention group achieved a greater reduction in SBP at 12 months (adjusted between-group difference: -3.14 mmHg, 95% CI: -5.24 to -1.03, <i>P</i> = 0.004). Subgroup analysis revealed significant heterogeneity by baseline SBP (interaction <i>P</i> < 0.001). For participants with baseline SBP below the median (<146 mmHg), the intervention group achieved a significantly larger SBP reduction (between-group difference: -6.79 mmHg, 95% CI: -9.62 to -3.96). It is expected that a decrease of 5 mmHg can reduce the risk of cardiovascular events by about 10%.

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Publication Details

Journal
Frontiers in Digital Health
Published
2026-01-26
DOI
https://doi.org/10.3389/fdgth.2025.1678235
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A randomized controlled trial on the application of a chronic disease management platform based on digital health technology combined with an innovative model of intelligent management for hypertension in patients with hypertension

K. Liu, Juying Lu, Lingyuan Zhang, Yuexia Gao et al.
Frontiers in Digital Health
Blood Pressure and Hypertension Studies
article

A randomized controlled trial on the application of a chronic disease management platform based on digital health technology combined with an innovative model of intelligent management for hypertension in patients with hypertension

K. Liu, Juying Lu, Lingyuan Zhang, Yuexia Gao, Xiaoyi Zhang, Benshan Niu
article en

Abstract

547 participants completed the study (Intervention: <i>n</i> = 273; Control: <i>n</i> = 274). The intervention group achieved a greater reduction in SBP at 12 months (adjusted between-group difference: -3.14 mmHg, 95% CI: -5.24 to -1.03, <i>P</i> = 0.004). Subgroup analysis revealed significant heterogeneity by baseline SBP (interaction <i>P</i> < 0.001). For participants with baseline SBP below the median (<146 mmHg), the intervention group achieved a significantly larger SBP reduction (between-group difference: -6.79 mmHg, 95% CI: -9.62 to -3.96). It is expected that a decrease of 5 mmHg can reduce the risk of cardiovascular events by about 10%.

Frontiers in Digital HealthVol. 7
Nantong University (CN), Affiliated Hospital of Nantong University (CN)
Openalex Percentile: Top 79%
Blood Pressure and Hypertension Studies
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A randomized controlled trial on the application of a chronic disease management platform based on digital health technology combined with an innovative model of intelligent management for hypertension in patients with hypertension — K. Liu, Juying Lu, et al. · Frontiers in Digital Health (2026) | TGRS Research Map | TGRS