Differential impacts of Helicobacter pylori antibody typing on gastric secretory function: a cross-sectional study based on serum biomarkers
H.pylori infection characteristically alters gastric functional serum markers in a virulence-dependent manner. These patterns biologically reflect the continuous pathological process from gastric mucosal inflammation to atrophy. Our findings underscore the clinical relevance of integrating H.pylori subtyping with gastric function assessment in gastric cancer risk screening, providing a novel perspective for the precise identification of high-risk individuals.
Authors
- Hongyuan Xu (ORCID: https://orcid.org/0000-0002-5558-1629)
- Chengning Yang
- Xue Liang (ORCID: https://orcid.org/0000-0001-8184-9011)
- Xiaotian Chen
- Chenliu Zhu
- Guangshi Zhong
- Xueping Zhao
- Yang Yang
Institutions
- Guangxi University (CN)
- ShenZhen People’s Hospital (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- Guangxi University of Chinese Medicine (CN)
- Qujiang People's Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1186/s12876-026-04611-0
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00