Clinical and Transcriptomic Response to Secukinumab in Korean Patients with Moderate-to-Severe Hidradenitis Suppurativa

Secukinumab demonstrated substantial clinical efficacy and modulated disease-relevant molecular pathways in Korean patients with moderate-to-severe HS. These findings support its therapeutic potential in Asian populations and provide mechanistic insights into IL-17 blockade in HS.

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Publication Details

Journal
Dermatology
Published
2026-01-26
DOI
https://doi.org/10.1159/000550262
Primary Topic
Hidradenitis Suppurativa and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical and Transcriptomic Response to Secukinumab in Korean Patients with Moderate-to-Severe Hidradenitis Suppurativa

H. D. Kim, Sujin Moon, J. Shin, Hee Jung Lee et al.
Dermatology
Hidradenitis Suppurativa and Treatments
article

Clinical and Transcriptomic Response to Secukinumab in Korean Patients with Moderate-to-Severe Hidradenitis Suppurativa

H. D. Kim, Sujin Moon, J. Shin, Hee Jung Lee, Dong Hyun Kim, Ji Hwan Moon, Jihee Kim, Hyun Ah Kwon, Jung Eun Kim
article en

Abstract

Secukinumab demonstrated substantial clinical efficacy and modulated disease-relevant molecular pathways in Korean patients with moderate-to-severe HS. These findings support its therapeutic potential in Asian populations and provide mechanistic insights into IL-17 blockade in HS.

Dermatology
Yonsei University (KR), Soonchunhyang University (KR), Samsung Medical Center (KR), CHA University Bundang Medical Center (KR), CHA University (KR)
Openalex Percentile: Top 78%
Hidradenitis Suppurativa and Treatments
DOISourceOpenAlex
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