KIF5B-driven unfolded protein response reprograms breast cancer immunosuppressive microenvironment for single-cell guided therapeutic targeting

Our multimodal analysis establishes KIF5B as a prognostic biomarker and potential therapeutic target in BRCA, with implications for understanding immune evasion and guiding precision treatment strategies.

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Publication Details

Journal
Discover Oncology
Published
2026-01-26
DOI
https://doi.org/10.1007/s12672-026-04526-y
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00
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article

KIF5B-driven unfolded protein response reprograms breast cancer immunosuppressive microenvironment for single-cell guided therapeutic targeting

Yu Xia, Panshi Zhang, Luo Zhiyong, Shuyu Li et al.
Discover Oncology
Protein Degradation and Inhibitors
article

KIF5B-driven unfolded protein response reprograms breast cancer immunosuppressive microenvironment for single-cell guided therapeutic targeting

Yu Xia, Panshi Zhang, Luo Zhiyong, Shuyu Li, Yue Liu
article en

Abstract

Our multimodal analysis establishes KIF5B as a prognostic biomarker and potential therapeutic target in BRCA, with implications for understanding immune evasion and guiding precision treatment strategies.

Discover OncologyVol. 17(1)
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 78%
Protein Degradation and Inhibitors
DOIOpen Access PDFOpenAlex
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KIF5B-driven unfolded protein response reprograms breast cancer immunosuppressive microenvironment for single-cell guided therapeutic targeting — Yu Xia, Panshi Zhang, et al. · Discover Oncology (2026) | TGRS Research Map | TGRS