Machine learning and SHAP-based interpretation of dietary antioxidants’ impact on comorbid MDD and suicidal ideation
The RF model exhibited superior predictive capability for comorbid MDD and SI. SHAP analysis highlighted the critical roles of dietary antioxidants, particularly vitamin C and kaempferol, in predicting these outcomes.
Authors
- Ting Fa Margherita Chang (ORCID: https://orcid.org/0000-0001-6762-4748)
- Jintao Wang (ORCID: https://orcid.org/0000-0001-5958-1194)
- Zhiwei Xu (ORCID: https://orcid.org/0000-0002-0625-1252)
- Yajing Li
- Hongling Jia
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- China-Japan Friendship Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1016/j.jad.2026.121252
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00