Chemotherapy-induced gut microbiota dysbiosis exacerbates cancer-related fatigue in breast cancer patients via neuroimmune-endocrine indicators
Baseline GM characteristics predict the risk and severity of chemotherapy-induced CRF, potentially through modulation of neuroimmune-endocrine pathways via gut-brain axis. These findings underscore the potential role of GM as a predictive biomarker and a therapeutic target for chemotherapy-induced CRF.
Authors
- Daoxia Guo (ORCID: https://orcid.org/0000-0002-4537-0705)
- Fengxia Lai (ORCID: https://orcid.org/0000-0003-3654-9006)
- Li Tian
- Haiyan Dong
- Zhongfang Yang
- Yang Yuan
Institutions
- Soochow University (TW)
- Soochow University (CN)
- 117th Hospital of People's Liberation Army (CN)
- People's Liberation Army 401 Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-26
- DOI
- https://doi.org/10.3389/fonc.2026.1710457
- Primary Topic
- Cancer-related cognitive impairment studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China