Rheumatoid arthritis and gout: a rare combination or overlooked coexistence?
RA and gout may overlap more than previously recognized, with stronger genetic evidence in SNRA. No causal effect on SUA suggests the link may not primarily involve urate pathways. Transcriptomic overlap in interferon signaling indicates potential molecular intersections, warranting further investigation.
Authors
- Kehu Yang (ORCID: https://orcid.org/0000-0001-7864-3012)
- Xiao Qiang Cai
- Zhihuang Chen
- Song Wei
- Tongtong Wu
- Shaowei Li
- Manli Wu
- Jingbei Zhang
- Wei Mao
- Xiaohong He
- Xueyin Chen
- Shuxin Li
- Qianying Zhao
- Linjie Song
- Xinfeng Guo
- Yan Yu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- General Hospital of Guangzhou Military Command (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1186/s13075-026-03746-5
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00