Low CD3+ and CD4+ T cell levels predict need for ventilatory support and in-hospital mortality in patients with COVID-19: a retrospective cohort study

Adaptive immunity, especially T CD3+ and T CD4+ cells, is relevant in the prognosis of COVID-19, and T-cell counts can help identify hospitalized COVID-19 patients at risk for severe outcomes: ventilatory support and in-hospital death.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-26
DOI
https://doi.org/10.3389/fmed.2026.1740358
Primary Topic
COVID-19 Clinical Research Studies
Type
article
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article

Low CD3+ and CD4+ T cell levels predict need for ventilatory support and in-hospital mortality in patients with COVID-19: a retrospective cohort study

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Low CD3+ and CD4+ T cell levels predict need for ventilatory support and in-hospital mortality in patients with COVID-19: a retrospective cohort study

Jose-Manuel Ramos-Rincón, Ester Lobato Martínez, Francisco Marco-de-la-Calle, Óscar Moreno-Pérez, Esperanza Merino-de-Lucas, Raquel García-Sevila, Rosario Sánchez-Martínez, Silvia Otero-Rodríguez
article en

Abstract

Adaptive immunity, especially T CD3+ and T CD4+ cells, is relevant in the prognosis of COVID-19, and T-cell counts can help identify hospitalized COVID-19 patients at risk for severe outcomes: ventilatory support and in-hospital death.

Frontiers in MedicineVol. 13
Universitat de Miguel Hernández d'Elx (ES), Hospital General Universitario de Alicante Doctor Balmis (ES)
Good health and well-being
Openalex Percentile: Top 76%
COVID-19 Clinical Research Studies
DOIOpen Access PDFOpenAlex
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