Effect of glucagon-like peptide-1 receptor agonists on heart rate in non-diabetic individuals with overweight or obesity: a systematic review and pairwise and network meta-analysis of randomized controlled trials
GLP-1RAs were associated with the increasing of HR in patients with overweight or obesity. Orforglipron 36 mg was associated with the most pronounced increase, and tirzepatide 5 mg the least.
Authors
- Hang Fu (ORCID: https://orcid.org/0000-0002-6121-4710)
- Chunhua Song (ORCID: https://orcid.org/0000-0001-6028-5923)
- Yiwen Zhang (ORCID: https://orcid.org/0000-0002-6928-8618)
- panpan cheng
- xuyang gong
- Linqi Diao
- Chuying Zhang
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Tongji Hospital (CN)
- Henan Provincial Center for Disease Control and Prevention (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1186/s40001-026-03933-9
- Primary Topic
- Heart rate and cardiovascular health
- Type
- article
- Field-Weighted Citation Impact
- 0.00