Sjögren's Disease and Cancer: Key Predictors From the Spanish Multicenter <scp>SjögrenSER</scp> ‐ <scp>TRANS</scp> Cohort

This study underscores the role of older age, glandular inflammation, and rituximab use as key risk factors for malignancy in SjD. However, the association with rituximab should be interpreted with caution, as indication bias cannot be ruled out. These findings emphasize the need for improved risk stratification and targeted surveillance strategies to facilitate early detection and enhance malignancy management in clinical practice. Prospective studies are warranted to refine monitoring protocols and optimize patient outcomes.

Authors

Institutions

Publication Details

Journal
Journal of Oral Pathology and Medicine
Published
2026-01-25
DOI
https://doi.org/10.1111/jop.70123
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Sjögren's Disease and Cancer: Key Predictors From the Spanish Multicenter SjögrenSER ‐ TRANS Cohort

Carlos Galisteo Lencastre, Ángel García‐Aparicio, Zulema Plaza, José Rosas et al.
Journal of Oral Pathology and Medicine
Salivary Gland Disorders and Functions
article

Sjögren's Disease and Cancer: Key Predictors From the Spanish Multicenter SjögrenSER ‐ TRANS Cohort

Carlos Galisteo Lencastre, Ángel García‐Aparicio, Zulema Plaza, José Rosas, Raúl Menor Almagro, M. Fernandez Castro, José Luis Andreu, Alejandro Olivé, Carlos Sánchez‐Piedra, Fernando Alonso, Javier Narvaez García, Victor Martínez‐Taboada, Susana Gil Barato, Olga Rusinovich‐Lovgach, part of the Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (EASSER) SJÖGRENSER Group, Jorge Gonzalez‐Martin, Francisco Javier Lopez Longo, Beatriz Rodrígez‐Lozano, Sara Manrique‐Arija, Ruth Lopez‐Gonzalez, Jesús Alberto Garcia‐Vadillo
article en

Abstract

This study underscores the role of older age, glandular inflammation, and rituximab use as key risk factors for malignancy in SjD. However, the association with rituximab should be interpreted with caution, as indication bias cannot be ruled out. These findings emphasize the need for improved risk stratification and targeted surveillance strategies to facilitate early detection and enhance malignancy management in clinical practice. Prospective studies are warranted to refine monitoring protocols and optimize patient outcomes.

Journal of Oral Pathology and Medicine
Universidad de Cantabria (ES), Universidad de Salamanca (ES), Hospital Universitario de Canarias (ES), Instituto de Salud Carlos III (ES), Bellvitge University Hospital (ES), ProMedica Toledo Hospital (US), Hospital General Universitario Gregorio Marañón (ES), Institut d'Investigació Biomédica de Bellvitge (ES), Marqués de Valdecilla University Hospital (ES), Hospital Universitario Puerta de Hierro Majadahonda (ES), Hospital Regional Universitario de Málaga (ES), Corporació Sanitària Parc Taulí (ES), Hospital Universitario de La Princesa (ES), Hospital Universitario HM Sanchinarro (ES), Hospital General Universitario de Alicante Doctor Balmis (ES), Spanish Society of Hematology and Hemotherapy (ES), Hospital Universitari Germans Trias i Pujol (ES), Hospital Jerez Puerta del Sur (ES), Hospital Marina Baixa (ES), Complejo Hospitalario Universitario de Toledo (ES), Universidad Autónoma de Madrid (ES), Universidad de Málaga (ES)
Sociedad Española de Reumatología
Good health and well-being
Openalex Percentile: Top 79%
Salivary Gland Disorders and Functions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.