Guiling prescription attenuates hyperuricemia via multi-target regulation of uric acid metabolism, renal protection, and inflammation: insights from metabolomics and network pharmacology
GP orchestrates uric acid metabolism through multi-target and multi-pathway regulation, highlighting its potential not only as a novel therapeutic strategy but also as a promising dietary supplement for the management of hyperuricemia.
Authors
- Yaxuan Guo
- Ying Wang (ORCID: https://orcid.org/0000-0002-9636-6300)
- Renjie Ding
- Huiwu Liu
- Huichun Zhao
- TianHui Zhou
- XiaoXia Gao
Institutions
- Shanxi University (CN)
- Shanxi Province Hospital of Traditional Chinese Medicine (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2026-01-26
- DOI
- https://doi.org/10.3389/fnut.2025.1738623
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00