Jugular foramen tumor causing isolated hypoglossal nerve palsy: a case report

Multisequence MRI confirmed compression of the hypoglossal nerve by a left jugular foramen tumor. This case is unique in that the tumor, despite its location, manifested solely as hypoglossal nerve palsy, an atypical presentation that can lead to misdiagnosis. This case report highlights the importance of high-resolution imaging and multidisciplinary collaboration in diagnosing skull base lesions and explores the anatomical relationship between the hypoglossal nerve and jugular foramen in disease pathogenesis.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-26
DOI
https://doi.org/10.3389/fonc.2026.1635494
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00

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article

Jugular foramen tumor causing isolated hypoglossal nerve palsy: a case report

Yirui Huang, Zhijun Wen, Jianhua CHENG, Youcheng Li
Frontiers in Oncology
Adrenal and Paraganglionic Tumors
article

Jugular foramen tumor causing isolated hypoglossal nerve palsy: a case report

Yirui Huang, Zhijun Wen, Jianhua CHENG, Youcheng Li
article en

Abstract

Multisequence MRI confirmed compression of the hypoglossal nerve by a left jugular foramen tumor. This case is unique in that the tumor, despite its location, manifested solely as hypoglossal nerve palsy, an atypical presentation that can lead to misdiagnosis. This case report highlights the importance of high-resolution imaging and multidisciplinary collaboration in diagnosing skull base lesions and explores the anatomical relationship between the hypoglossal nerve and jugular foramen in disease pathogenesis.

Frontiers in OncologyVol. 16
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Wenzhou Hospital of Traditional Chinese Medicine (CN)
Science and Technology Plan Project of Wenzhou, China
Openalex Percentile: Top 78%
Adrenal and Paraganglionic Tumors
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