Case Report: A case of myocardial calcification combined with abnormal Q waves on electrocardiogram

We report a rare case of focal myocardial calcification with pathological Q waves in a maintenance dialysis patient. Chronic kidney disease (CKD)-related disturbances of calcium-phosphate metabolism can cause metastatic myocardial calcification. Severe focal calcification may produce mechanical compression and cell necrosis, disrupt electrical coupling, create electrically silent zones, and result in pathological Q waves. In CKD patients with abnormal ECG findings, myocardial calcification should be included in the differential diagnosis and evaluated using imaging and metabolic data.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-26
DOI
https://doi.org/10.3389/fcvm.2025.1745357
Primary Topic
Pericarditis and Cardiac Tamponade
Type
article
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article

Case Report: A case of myocardial calcification combined with abnormal Q waves on electrocardiogram

Dan Li, Dong Li
Frontiers in Cardiovascular Medicine
Pericarditis and Cardiac Tamponade
article

Case Report: A case of myocardial calcification combined with abnormal Q waves on electrocardiogram

Dan Li, Dong Li
article en

Abstract

We report a rare case of focal myocardial calcification with pathological Q waves in a maintenance dialysis patient. Chronic kidney disease (CKD)-related disturbances of calcium-phosphate metabolism can cause metastatic myocardial calcification. Severe focal calcification may produce mechanical compression and cell necrosis, disrupt electrical coupling, create electrically silent zones, and result in pathological Q waves. In CKD patients with abnormal ECG findings, myocardial calcification should be included in the differential diagnosis and evaluated using imaging and metabolic data.

Frontiers in Cardiovascular MedicineVol. 12
Jiangmen Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 80%
Pericarditis and Cardiac Tamponade
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