TMIGD2 in Bladder Cancer: A Bioinformatics and Experimental Approach to Understanding its Prognostic and Therapeutic Potential

This study demonstrates that TMIGD2 is downregulated in BLCA and correlates with adverse prognosis and immune regulation. Its potential as a prognostic biomarker and therapeutic target is underscored by its involvement in key pathways, immune infiltration, and drug sensitivity. Further research is essential to fully realize the clinical potential of TMIGD2 in the management of BLCA.

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Publication Details

Journal
Current Topics in Medicinal Chemistry
Published
2026-01-15
DOI
https://doi.org/10.2174/0115680266414071251126071447
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

TMIGD2 in Bladder Cancer: A Bioinformatics and Experimental Approach to Understanding its Prognostic and Therapeutic Potential

Mingfeng Shen, Zuomin Wang, Yiwen Chen, Zhihai Wu et al.
Current Topics in Medicinal Chemistry
Ferroptosis and cancer prognosis
article

TMIGD2 in Bladder Cancer: A Bioinformatics and Experimental Approach to Understanding its Prognostic and Therapeutic Potential

Mingfeng Shen, Zuomin Wang, Yiwen Chen, Zhihai Wu, Dongbing Li, Meiting Lao, Wenxia Chen, Wangdong Deng
article en

Abstract

This study demonstrates that TMIGD2 is downregulated in BLCA and correlates with adverse prognosis and immune regulation. Its potential as a prognostic biomarker and therapeutic target is underscored by its involvement in key pathways, immune infiltration, and drug sensitivity. Further research is essential to fully realize the clinical potential of TMIGD2 in the management of BLCA.

Current Topics in Medicinal ChemistryVol. 26
Soochow University (CN), Longgang Central Hospital (CN)
No poverty
Openalex Percentile: Top 79%
Ferroptosis and cancer prognosis
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