Design, Synthesis, Bioactivity, and Docking Studies of Isatin-Hydrazone Derivatives as Potential CDK-2 Inhibitors

These novel isatin-hydrazone derivatives, particularly 2e, 2f, and 2h, could be used as potential anticancer agents that inhibit CDK2 kinase activity.

Authors

Institutions

Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2026-01-15
DOI
https://doi.org/10.2174/0118715206420750251029040513
Primary Topic
Cancer-related Molecular Pathways
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Design, Synthesis, Bioactivity, and Docking Studies of Isatin-Hydrazone Derivatives as Potential CDK-2 Inhibitors

Kaige Guo, Xiaofen Liao, Ye Tao, Guobing Yan
Anti-Cancer Agents in Medicinal Chemistry
Cancer-related Molecular Pathways
article

Design, Synthesis, Bioactivity, and Docking Studies of Isatin-Hydrazone Derivatives as Potential CDK-2 Inhibitors

Kaige Guo, Xiaofen Liao, Ye Tao, Guobing Yan
article en

Abstract

These novel isatin-hydrazone derivatives, particularly 2e, 2f, and 2h, could be used as potential anticancer agents that inhibit CDK2 kinase activity.

Anti-Cancer Agents in Medicinal ChemistryVol. 26
Shaanxi Provincial People's Hospital (CN), Jiyang College of Zhejiang A&F University (CN)
Openalex Percentile: Top 78%
Cancer-related Molecular Pathways
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Design, Synthesis, Bioactivity, and Docking Studies of Isatin-Hydrazone Derivatives as Potential CDK-2 Inhibitors — Kaige Guo, Xiaofen Liao, et al. · Anti-Cancer Agents in Medicinal Chemistry (2026) | TGRS Research Map | TGRS