The Mediating Role of Immune Cells in the Genetically Predicted Relationship between Gut Microbiota and Puerperal Sepsis: A Mendelian Randomization Study

This study provides evidence of a causal relationship between the abundance of certain gut microbiota species and PS, while also revealing a potential mediating role of immune cells. These findings offer valuable theoretical insights into personalized treatment strategies and the development of novel diagnostic biomarkers for PS.

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Publication Details

Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2026-01-15
DOI
https://doi.org/10.2174/0118715303415101251129044507
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

The Mediating Role of Immune Cells in the Genetically Predicted Relationship between Gut Microbiota and Puerperal Sepsis: A Mendelian Randomization Study

YiHui Chai, Jun Li, Chunsong Gu, Qian Li et al.
Endocrine Metabolic & Immune Disorders - Drug Targets
Gut microbiota and health
article

The Mediating Role of Immune Cells in the Genetically Predicted Relationship between Gut Microbiota and Puerperal Sepsis: A Mendelian Randomization Study

YiHui Chai, Jun Li, Chunsong Gu, Qian Li, Jianjun Niu, Zhiliang Fan, Xiang Pu, Chunyan Liu
article en

Abstract

This study provides evidence of a causal relationship between the abundance of certain gut microbiota species and PS, while also revealing a potential mediating role of immune cells. These findings offer valuable theoretical insights into personalized treatment strategies and the development of novel diagnostic biomarkers for PS.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 26
Guiyang College of Traditional Chinese Medicine (CN), Affiliated Hospital of Guizhou Medical University (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 78%
Gut microbiota and health
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