Problems of Vitamin D Deficiency Associated with Women’s Infertility

Abstract Background: When exposed to UV radiation, the skin produces vitamin D, a lipid-soluble vitamin. Because of the receptors of vitamin D are located in reproductive organs such as the endometrium, ovary, and uterus, researchers can develop theories about its role in reproduction. The role of vitamin D in fertility has been shown in a variety of animal experiments. However, human studies have not consistently confirmed vitamin D’s effect on infertility. Objectives: The major goal of this research was to define the prevalence of vitamin D deficiency among Wasit women and its effect on infertility, with a focus on those who were experiencing primary or secondary infertility. Materials and Methods: Samples were collected from 60 females with primary infertility, 60 women with secondary infertility, and 60 fertile women with at least one child, and were recruited from February to May 2023, then divided into three age groups, the first group (15‐25 years), the second group (26‐35 years), and the third group (>35 years). The levels of vitamin D were measured using the enzyme-linked immunosorbent assay. Results: It was found that vitamin D deficiency was rather common, with the greatest rates occurring in those aged 35 and older (40% for women with primary infertility and 53% for those with secondary infertility). Primary and secondary infertility rates were each 20% lower in the second age group (26‐35 years). Conclusion: The current study found a high prevalence of vitamin D deficiency in women suffering from primary and secondary infertility in Wasit Governorate. Therefore, women who suffer from infertility may benefit from examining their levels of vitamin D because it may be one of the causes of infertility, which can be easily treated by taking vitamin D supplements.