Capecitabine with or without bevacizumab as maintenance therapy in metastatic colorectal cancer: a real-world retrospective study in Vietnamese patients

In this first real-world study from Vietnam, maintenance therapy with bevacizumab plus capecitabine significantly improved PFS compared to capecitabine alone, with acceptable safety. These findings support the use of biologic-based maintenance strategies in appropriate patients and provide valuable evidence for guiding mCRC treatment in resource-constrained settings.

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Publication Details

Journal
Postgraduate Medicine
Published
2026-01-02
DOI
https://doi.org/10.1080/00325481.2026.2619220
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Capecitabine with or without bevacizumab as maintenance therapy in metastatic colorectal cancer: a real-world retrospective study in Vietnamese patients

Phuong Thanh Pham, Thang Q. Tran, Que Thi Pham, Cuc Thi Hoang et al.
Postgraduate Medicine
Colorectal Cancer Treatments and Studies
article

Capecitabine with or without bevacizumab as maintenance therapy in metastatic colorectal cancer: a real-world retrospective study in Vietnamese patients

Phuong Thanh Pham, Thang Q. Tran, Que Thi Pham, Cuc Thi Hoang, T. Tran, Huy Van Nguyen, Kim Anh Thi Nguyen, Tan Ngoc Hoang
article en

Abstract

In this first real-world study from Vietnam, maintenance therapy with bevacizumab plus capecitabine significantly improved PFS compared to capecitabine alone, with acceptable safety. These findings support the use of biologic-based maintenance strategies in appropriate patients and provide valuable evidence for guiding mCRC treatment in resource-constrained settings.

Postgraduate MedicineVol. 138(1)
Hanoi Medical University (VN), Vietnam National Children's Hospital (VN)
Good health and well-being
Openalex Percentile: Top 79%
Colorectal Cancer Treatments and Studies
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Capecitabine with or without bevacizumab as maintenance therapy in metastatic colorectal cancer: a real-world retrospective study in Vietnamese patients — Phuong Thanh Pham, Thang Q. Tran, et al. · Postgraduate Medicine (2026) | TGRS Research Map | TGRS