Early mechanical reperfusion in high-risk pulmonary embolism supported by venoarterial extracorporeal membrane oxygenation: a multicenter international cohort study
In this large international cohort of patients with high-risk PE on V-A ECMO, early mechanical reperfusion therapy was not associated with a reduction in 90-day mortality or ECMO duration. These findings may support a stepwise, individualized approach favoring initial ECMO stand-alone support, although a certain clinical benefit from early mechanical reperfusion in selected patients cannot be excluded.
Authors
- C. Guervilly
- Matthieu Petit (ORCID: https://orcid.org/0000-0003-3267-9938)
- Baptiste Compagnon
- PM Lepper
- Antoine Beurton (ORCID: https://orcid.org/0000-0002-3708-4653)
- Pierre Denormandie
- H. Winiszewski
- Guido Tavazzi
- Maria Heinrich
- Thibault Duburcq (ORCID: https://orcid.org/0000-0002-9073-7676)
- J Chico
- Alexander Dietl (ORCID: https://orcid.org/0000-0002-4091-8620)
- Louis Pot
- Joshua Ihle (ORCID: https://orcid.org/0000-0001-7867-3713)
- Alice Vennier
- Lise Thellier
- Philip S. Fortuna
- M. Balik
- Dirk Donker
- Adrien Werquin (ORCID: https://orcid.org/0009-0000-1229-207X)
- A. Mansour
- Raphael Giraud
- Jonathan Taylor
- Thomas Mueller
- Marco Giani
- CATAPULTE Investigator Group
- Anna Condella
- Celine Besnard
- Paul Masi
- Jae-Seung Jung
- Fabio Silvio Taccone
- Sally Newman
- Marc Pierrot
- Jordi Riera
- Zied Ltaief
- Dieter Dauwe
- Benjamin Assouline
- David Levy
- Julien Dessajan
- Shinichiro Ohshimo
- Matthieu Schmidt
- Roberto Roncon-Albuquerque
- Giacomo Grasselli
- Alain Combes
- Hélène Nougué
- Pauline Yeung Ng
- Guillaume Lebreton
Institutions
- Hiroshima University (JP)
- Université Libre de Bruxelles (BE)
- Inserm (FR)
- University of Toronto (CA)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- University of Washington (US)
- Université Paris Cité (FR)
- Charles University (CZ)
- The Alfred Hospital (AU)
- University Hospital Complex Of Vigo (ES)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Hospital de São João (PT)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- University Medical Center Utrecht (NL)
- Centre Hospitalier Universitaire de Lille (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Université Rennes 2 (FR)
- University Hospital Regensburg (DE)
- Sorbonne Université (FR)
- St Vincent's Hospital Sydney (AU)
- Assistance Publique Hôpitaux de Marseille (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Hospital de São José (PT)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Hôpital Européen (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
- Hôpital Nord (FR)
- Hôpital Marie Lannelongue (FR)
- Hôpital Rangueil (FR)
- Hôpital Pontchaillou (FR)
- Vall d'Hebron Hospital Universitari (ES)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Paris Cardiovascular Research Center (FR)
- Hôpital Ambroise-Paré (FR)
- Centre hospitalier universitaire d'Orléans (FR)
- Hôpital Bichat-Claude-Bernard (FR)
- Unité de recherche sur les maladies cardiovasculaires et métaboliques (FR)
- Policlinico San Matteo Fondazione (IT)
- Centre Hospitalier Universitaire de Rennes (FR)
- Korea University (JP)
- French Clinical Research Infrastructure Network (FR)
- Geneva College (US)
- University of Milano-Bicocca (IT)
- University of Hong Kong (HK)
- Saarland University (DE)
- Nantes Université (FR)
- University of Lausanne (CH)
- KU Leuven (BE)
Publication Details
- Journal
- American Journal of Respiratory and Critical Care Medicine
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1093/ajrccm/aamaf116
- Citations
- 1
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 21.28