Mucus plugs in chronic obstructive pulmonary disease are heterogeneous in size and shape and occur in relatively large airways
COPD is characterized by mucus plugs of varying size and shape and emphysematous lung regions may be differentially susceptible to formation of these plugs. The location of mucus plugs in segmental and subsegmental airways in COPD makes them amenable to treatment with inhaled medications or bronchoscopy.
Authors
- Jessica Bon
- Igor Barjaktarevic
- B J Huang
- Lewis D. Hahn (ORCID: https://orcid.org/0000-0003-0468-9442)
- Kimberly Kallianos (ORCID: https://orcid.org/0000-0001-5690-4971)
- Brett M. Elicker (ORCID: https://orcid.org/0000-0001-6188-9622)
- Omar Farooqui
- R Paine
- Travis Henry
- JOHN V. FAHY
- J Michael Wells
- MeiLan K Han
- R Graham Barr
- Prescott G Woodruff
- Benjamin M Smith
- Nadia Hansel
- Alejandro P Comellas
Institutions
- University of Iowa (US)
- Mayo Clinic (US)
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- Duke University (US)
- University of California, San Francisco (US)
- University of Utah (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- University of California System (US)
- University of Alabama at Birmingham (US)
- Michigan Medicine (US)
- Mayo Clinic in Arizona (US)
- Duke Medical Center (US)
- University of Iowa Health Care (US)
- Mayo Clinic in Florida (US)
- Duke University Hospital (US)
- Wake Forest University (US)
Publication Details
- Journal
- American Journal of Respiratory and Critical Care Medicine
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1093/ajrccm/aamaf138
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 36.44