Cardiovascular Risk Associated with Polypharmacy in Heart Failure: A Systematic Review and Meta-Analysis

Polypharmacy in patients with HF was associated with increased risk of composite CV outcome and HF hospitalization, reflecting the complexity of managing multiple medications. These findings underscore the need for individualized medication reviews to minimize inappropriate prescribing and ensure continued delivery of evidence-based therapies.

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Publication Details

Journal
ESC Heart Failure
Published
2026-01-22
DOI
https://doi.org/10.1093/eschf/xvag005
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Cardiovascular Risk Associated with Polypharmacy in Heart Failure: A Systematic Review and Meta-Analysis

Minseo Kim, Sunny Kumar, Gerald Chi, Jane J Lee
ESC Heart Failure
Heart Failure Treatment and Management
article

Cardiovascular Risk Associated with Polypharmacy in Heart Failure: A Systematic Review and Meta-Analysis

Minseo Kim, Sunny Kumar, Gerald Chi, Jane J Lee
article en

Abstract

Polypharmacy in patients with HF was associated with increased risk of composite CV outcome and HF hospitalization, reflecting the complexity of managing multiple medications. These findings underscore the need for individualized medication reviews to minimize inappropriate prescribing and ensure continued delivery of evidence-based therapies.

ESC Heart Failure
Beth Israel Deaconess Medical Center (US), Sookmyung Women's University (KR), United Health Services (US)
Good health and well-being
Openalex Percentile: Top 80%
Heart Failure Treatment and Management
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