Natural Product-Based Virtual Screening Identifies Potential Inhibitors ofFeline Coronavirus 3CLpro

The findings indicated the compounds' strong potential for further development as antiviral leads. The results also revealed several core molecular frameworks that may serve as an initial reference for designing FCoV 3CLpro inhibitors, laying the groundwork for structure-guided drug discovery efforts.

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Publication Details

Journal
Current Topics in Medicinal Chemistry
Published
2026-01-14
DOI
https://doi.org/10.2174/0115680266426906251125112131
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Natural Product-Based Virtual Screening Identifies Potential Inhibitors ofFeline Coronavirus 3CLpro

Ren Kong, Yingguang Zhu, Weihua Zhang, Zunyun Jiang et al.
Current Topics in Medicinal Chemistry
Computational Drug Discovery Methods
article

Natural Product-Based Virtual Screening Identifies Potential Inhibitors ofFeline Coronavirus 3CLpro

Ren Kong, Yingguang Zhu, Weihua Zhang, Zunyun Jiang, Wang Xiong, Hongyi Chen
article en

Abstract

The findings indicated the compounds' strong potential for further development as antiviral leads. The results also revealed several core molecular frameworks that may serve as an initial reference for designing FCoV 3CLpro inhibitors, laying the groundwork for structure-guided drug discovery efforts.

Current Topics in Medicinal ChemistryVol. 26
Nanjing Agricultural University (CN), Jiangsu University of Technology (CN), Public Risk Management Association (US)
Good health and well-being
Openalex Percentile: Top 77%
Computational Drug Discovery Methods
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Natural Product-Based Virtual Screening Identifies Potential Inhibitors ofFeline Coronavirus 3CLpro — Ren Kong, Yingguang Zhu, et al. · Current Topics in Medicinal Chemistry (2026) | TGRS Research Map | TGRS