Explore the Role of Choline in the Pathogenesis of Neural Tube Defects

Choline and its derivatives are essential for neural tube development. Choline deficiency is an important potential risk factor for neural tube defects, especially in the context of folic acid supplementation, and choline supplementation during pregnancy may be effective in reducing its risk.

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Publication Details

Journal
Birth Defects Research
Published
2026-01-22
DOI
https://doi.org/10.1002/bdr2.70019
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Explore the Role of Choline in the Pathogenesis of Neural Tube Defects

Siyu Chen, LinXiao Wan, Shuyue Deng, Lan Kang et al.
Birth Defects Research
Folate and B Vitamins Research
article

Explore the Role of Choline in the Pathogenesis of Neural Tube Defects

Siyu Chen, LinXiao Wan, Shuyue Deng, Lan Kang, Xinyi Liu, Wenbin Dong
article en

Abstract

Choline and its derivatives are essential for neural tube development. Choline deficiency is an important potential risk factor for neural tube defects, especially in the context of folic acid supplementation, and choline supplementation during pregnancy may be effective in reducing its risk.

Birth Defects ResearchVol. 118(2)
Affiliated Hospital of Southwest Medical University (CN), First Affiliated Hospital of Sichuan Medical University (CN)
Openalex Percentile: Top 80%
Folate and B Vitamins Research
DOISourceOpenAlex
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