Design of Experiments-Based Formulation and Optimization of Oxaliplatin-Loaded Solid Lipid Nanoparticles for the Management of Colorectal Cancer
The optimized Oxaliplatin SLNs demonstrated improved solubility, controlled release, and enhanced cytotoxicity, confirming their promise as a nanocarrier system for colorectal cancer therapy. Further in vivo studies are required to validate clinical effectiveness.
Authors
- Kousalya Selvaraj
- Jey Kumar Pachiyappan (ORCID: https://orcid.org/0000-0002-7882-9287)
- Imrankhan Nizam (ORCID: https://orcid.org/0000-0003-0483-7927)
- Parikshit Roychowdhury (ORCID: https://orcid.org/0000-0002-3248-6645)
- Samanwita Khanra (ORCID: https://orcid.org/0009-0007-0306-7939)
- G. Kuppusamy
- Nihar Ranjan Bhuyan
- Roshan P. Rao
Institutions
- JSS Academy of Higher Education and Research (IN)
- Sikkim University (IN)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2026-01-12
- DOI
- https://doi.org/10.2174/0115680096414252251125053406
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00