Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer
In biopsy patients, the LOY levels in the cancer group were higher than those in the normal group, and this was more pronounced in patients at advanced clinical stages. LOY levels have strong diagnostic efficacy for PCa, indicating that LOY may serve as an auxiliary biomarker for early PCa diagnosis.
Authors
- Yan Lu (ORCID: https://orcid.org/0000-0002-8455-5358)
- Tsuyoshi Hachiya (ORCID: https://orcid.org/0000-0002-5274-3266)
- Masayoshi Nagata (ORCID: https://orcid.org/0000-0002-3077-191X)
- Hisamitsu Ide (ORCID: https://orcid.org/0000-0001-6350-9814)
- Haruhiko Wakita (ORCID: https://orcid.org/0009-0009-7312-5967)
- Yoshihiro Ikehata (ORCID: https://orcid.org/0000-0002-6706-2359)
- Takuro Kobayashi
- Yiming Jin
- Jun Lu
- Shigeo Horie
- Yasunari Tanaka
Institutions
- Juntendo University (JP)
- University of Virginia (US)
Publication Details
- Journal
- The Prostate
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1002/pros.70128
- Citations
- 1
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 30.93