Multi-omics insights into gut microbial dysbiosis and metabolic alterations in immune checkpoint inhibitor-induced thrombocytopenia
The depletion of arginine and associated metabolic disruptions are associated with ICIs-TCP and may represent a potential therapeutic target for mitigating TCP risk in patients receiving ICIs.
Authors
- Yunfeng Cheng (ORCID: https://orcid.org/0009-0007-1332-3916)
- Bei Xu
- Peng Liu
- Tao Wang
- Ling Liu
- Na Yan
Institutions
- Fudan University (CN)
- Dian Diagnostics (China) (CN)
Publication Details
- Journal
- Immunotherapy
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1080/1750743x.2026.2618937
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00