Differential Neutrophil and Eosinophil Infiltrations in the Sub-Lining Compartment of Rheumatoid Versus Osteoarthritic Synovium

Increased neutrophilic infiltrations and the presence of eosinophils in synovial sub-lining compartment discriminate RA from OA. Studies to elucidate the contribution of innate immunity cells to the pathophysiology of joint destruction in RA through interactions with fibroblasts are warranted.

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Publication Details

Journal
Mediterranean Journal of Rheumatology
Published
2025-12-01
DOI
https://doi.org/10.31138/mjr.050225.hre
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Differential Neutrophil and Eosinophil Infiltrations in the Sub-Lining Compartment of Rheumatoid Versus Osteoarthritic Synovium

Maria G. Tektonidou, Anastasios Mourikis, Alkiviadis Vossos, George E. Fragoulis et al.
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Differential Neutrophil and Eosinophil Infiltrations in the Sub-Lining Compartment of Rheumatoid Versus Osteoarthritic Synovium

Maria G. Tektonidou, Anastasios Mourikis, Alkiviadis Vossos, George E. Fragoulis, Maria Sakkou, Ilias Fanourgiakis, Petros P. Sfikakis
article en

Abstract

Increased neutrophilic infiltrations and the presence of eosinophils in synovial sub-lining compartment discriminate RA from OA. Studies to elucidate the contribution of innate immunity cells to the pathophysiology of joint destruction in RA through interactions with fibroblasts are warranted.

Mediterranean Journal of RheumatologyVol. 36(4)
National and Kapodistrian University of Athens (GR), KAT General Hospital of Attica (GR)
Reduced inequalities
Openalex Percentile: Top 24%
Rheumatoid Arthritis Research and Therapies
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