Short-term Outcomes of Lateral Pancreaticojejunostomy in Patients with Chronic Pancreatitis: A Case Series from a Tertiary Care Center

A BSTRACT Background: Chronic pancreatitis (CP) is a debilitating condition characterized by irreversible pancreatic damage, leading to pain & significant morbidity. Methods: This case series analyzes the short-term outcomes of 20 patients having CP with intractable pain & ductal dilatation who underwent lateral pancreaticojejunostomy (LPJ) at a tertiary care center from January 2022 to May 2025. The cohort predominantly consistes of young males, with idiopathic and alcohol-related etiologies being the most common. Preoperative evaluations included clinical assessments and imaging studies to determine the presence of ductal dilation and other complications. Results: Surgical intervention involved LPJ, which provided substantial postoperative pain relief, with 90% of patients reporting complete resolution of symptoms. Nutritional recovery was also notable, with 90% of patients experiencing significant weight gain within the first few months post-surgery. The overall complication rate was low, with no major adverse events or mortality. Conclusion: This study underscores the efficacy and safety of LPJ as a viable surgical option for managing chronic pancreatitis, particularly in patients with dilated main pancreatic ducts. The findings contribute valuable insights into the management of CP in diverse populations and highlight the need for further long-term studies to assess the durability of these outcomes.